Posted on Leave a comment

Nordic Oil Launches New Line of Products: How Can CBD Benefit Your Pet?

While CBD is increasingly popular among us human beings for managing and reducing pain, discomfort as well as mood, now pets are also being treated with CBD! Nordic Oil has launched a new line of CBD products specific to pets including oils and supplement tablets for cats and dogs. (Products for horses are coming soon!) Before you approach your veterinarian, we recommend catching up on some important facts!

This article assumes that you, the reader, are already familiar with CBD. If not, please first read our page Cannabidiol: The Ultimate Guide to CBD, which lists four main ways of taking CBD.

Why Administer CBD to Your Pet

as oppose to other drugs

There are a number of properties in CBD supplements that pets can benefit from.

A generally strong endocannabinoid system is vital in treating any ailment. CBD, acting as an adptogen, modulates the endocannabinoid system, stabilizing the physiological processes and promoting homeostasis. Cats and dogs have well developed endocannabinoid systems just like humans. To review our Cannabidiol: The Ultimate Guide to CBD, it’s important to understand the relationship between the nervous system and the endocannabinoid system. The endocannabinoid system is involved in regulating pain, immune system, sleep, appetite and much more. So in other words, the body produces endocannabinoids that bind to cannabinoid receptors in your nervous system. CB1 receptors are located in the nervous system (connective tissues, gonads, glands and organs) but there are also CB2 receptors in the immune system (spleen, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands and reproductive organs), which is why scientists are, for instance, fascinated with the benefits of CBD for inhibiting the growth of tumors. (Researchers today suspect that there may even be a third cannabinoid receptor which has yet to be discovered!) In other words, the endocannabinoid system regulates many bodily functions. The peculiarity of the cannabinoid receptors is their location. To explain, your nervous system is built of transmitters and receptors, i.e. first and secondary cells. So, normally, receptors are located at the secondary cell to forward the signal on. However, oddly, the cannabinoid receptors are located on the former, i.e. the transmitter cell. This means that CBD is not directly responsible for the forwarding of the signal, but the transmitter cell retrograde, that is, returns information in a retrograde manner. Cannabinoids thus provide feedback to the transmitter cell. The messengers of the endocannabinoid system are therefore referred to as retrograde neurotransmitters or neuromodulators. So although CBD has little direct binding affinity for CB1 and CB2 receptors, it can influence the actual information transferred, also modulating several non-cannabinoid receptors and ion channels. Essentially, CBD works alongside the CB1 and CB2 receptors, supporting your whole endocannabinoid system, such as by enhancing or inhibiting the binding action of certain G-protein coupled receptors. For example, Jose Alexandre Crippa and his colleagues at the University of San Paulo in Brazil and King’s College in London have found that CBD directly activates the 5-HT1A (hydroxytryptamine) serotonin receptor, thereby conferring an anti-anxiety effect. Another example, CBD binds to TRPV1 receptors, which also function as ion channels, TRPV1 being known for mediating pain perception, inflammation and body temperature.

CBD is also a rich source of Omega fatty acids, amino acids, vitamins, terpenes and chlorophyll. This could help to fulfill the nutritional gaps of your pet’s diet.

Remember that CBD is completely safe. It does not have psychoactive effects like THC, its sister to the Cannabis plant. It is non-toxic. At Nordic Oil, all of their oils come from certified hemp plants, organically grown, and therefore GMO-free – meaning they are free of chemical fertilizers and growth hormones – plus they are gluten free and do not contain any artificial preservatives or dyes. Therefore, research and reviews praise CBD as a healthy choice for animals.

What is The Dosage Of CBD Oil For Dogs?

With the variety of online sources available, often claiming different methods/approaches, it may be stressful in figuring out the right dosage of CBD for your dog or cat. For trusty resources, we recommend our own website; Medical Marijuana, Inc., a subsidiary of Phyto Animal Health, which has introduced pet-friendly CBD products; as well as Nordic Oil, which clearly states the following:

Regarding dosages of CBD: We always advice to start with a small dose. It is very important to become familiar with how your pet responds to CBD before increasing the dose, which should be done gradually until symptoms improve.

Regarding Oils for Cats and Dogs: For adult cats, we recommend starting with 1-2 drops, which can be given 2-3 times a day. For kittens, 1 drop can be given 1-2 times a day. For adult dogs, we recommend starting with 2-3 drops per 10 kg body weight, which can be given 2-3 times a day. For puppies, 1-2 drops can be given 1-2 times a day. The concentrates can be mixed with other foods or liquids for consumption. We recommend fatty foods such as cheese.

Regarding Supplement Tablets for Cats and Cogs: For adult cats, we recommend starting with 1-2 tablets per day. For kittens, 1 tablet can be administered per day. For adult dogs, we recommend starting with 2 to a maximum of 6 tablets per 10 kg body weight per day. For puppies, 2-3 tablets can be administered per day.

Similarly, on the Phyto Animal Health website, recommends a daily dosage of 01-0.5 milligram split into two servings for each kilogram of your dog’s body weight. Hence if you are dog weighs 4.5 kilograms, the recommended usage would be two servings ranging from 0.45 to 2.25 milligrams per day of CBD. However, you and your veterinarian are more fit to determine the right dosage for your pet dog. You might be surprised how well your dog respond with a lower dosage, for instance. (Phyto Animal Health offers a 1 oz. bottle of 100 mg of CBD and a 2 oz. bottle of 500 mg of CBD.)

Note: Serving Sizes Vis-à-vis FDA Recommended Dosages

When it comes to dietary supplements for pets, they are regulated by the FDA (Food and Drug Administration). This is as per the stipulations and requirements of the Federal Food, Drug & Cosmetic Act. FDA classifies all supplement as feed supplements. However, the FDA has not come out with any recommended daily dosage or service size for CBD concerning pets.

Original Article

Posted on Leave a comment

Quick Hits

Some recent highlights and curiosities from the amazing world of cannabis science and therapeutics:

  • CBD and autism. In his first article of the new year, Raphael Mechoulam and other Israeli scientists look at the “real life experiences of medical cannabis treatment in autism.” Published in Nature, the study found that just under a third of patients report significant improvements and over half report moderate improvements while using CBD-rich oil derived from cannabis (30% CBD, 1-2% THC). The improvements include decreased aggression and agitation, fewer seizures, and better sleep, appetite and ability to concentrate. Around 10-20% of patients stopped taking various medications (mostly antipsychotic and antiepileptic drugs) within 6 months of starting cannabis treatment. One quarter of people experienced some negative side effects like sedation or restlessness, but none were severe. And about one in 5 stopped treatment because it wasn’t effective. Even though there remains a lot to be discovered about how and why CBD can improve the lives of people with autism, it is clear that cannabis can be used safely by this population and should be studied further.
  • Cannabis and ADHD. A study in Molecular Psychiatry with tens of thousands of people found an association between ADHD and cannabis use. Their data suggests that ADHD causes later cannabis use, which may support the notion that THC is used to self medicate (although ADHD is associated with heavier use of many drugs). Previous research has found that THC may be effective for some cases that do not respond well to Ritalin.
  • Self medicating for endometriosis. Endometriosis is a poorly-understood condition causing severe chronic pain and alterations in a woman’s menstrual cycle. As an understudied disease, treatment is limited. Scientists surveyed over 400 Australian women to see what actions they took to treat their pelvic pain. Cannabis, heat, CBD oil, and dietary changes were rated most effective by women, in that order. Unfortunately, more women used alcohol than cannabis to manage symptoms; self-medicating with alcohol promotes chronic inflammation and led to worsening pain and fatigue in over half of such women. This underscores the importance of not treating cannabis like alcohol in the ongoing saga of legalization. (Note: endometriosis is diagnosed with an invasive surgical procedure, and so many women who likely have endometriosis go undiagnosed. The group that responded to this survey had a confirmed diagnosis.)
  • Concussions and alcoholism. Traumatic brain injury (TBI) leads to numerous problems, including alcoholism and suicide. New findings indicate that endocannabinoids aid TBI recovery: When researchers boosted 2-AG levels shortly after injury, rats displayed less anxiety and less interest in alcohol. This is significant since alcoholism is a serious comorbidity of brain injury. The researchers link the protective effect of 2-AG to changes in glutamate transmission in the central amygdala, the part of the brain that processes traumatic and fearful memories. Other preclinical research has demonstrated that endocannabinoids can play a protective role after traumatic brain injuries, like concussion, by ameliorating glutamatergic toxicity.

Original Article

Posted on Leave a comment

Project CBD Releases Educational Primer on Cannabinoid-Drug Interactions

New: This report is now available in Spanish and Japanese translations! See bottom of this article for downloads.

Project CBD, a California-based educational non-profit, has published an in-depth primer on Cannabinoid-Drug Interactions for health professionals, patients, and public policy-makers. The 33-page report, summarized below, is available for free download at the bottom of the page.

Original Article